My computer been infected with TROJAN HORSES please help me.

spikehamc: C:\Program Files\Google\Google Desktop Search\GoogleDesktop.exe C:\Program Files\Trend Micro\Virus Buster 14\pccguide.exe C:\Windows\System32\spool\drivers\w32×86\3\hpztsb10.exe C:\Program Files\Sharp\Sharpdesk\SharpTray.exe …

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